Quarterly report pursuant to Section 13 or 15(d)

Fair Value of Warrants - Assumptions Used in Computing Fair Value of Derivative Warrants (Details)

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Fair Value of Warrants - Assumptions Used in Computing Fair Value of Derivative Warrants (Details) - $ / shares
3 Months Ended 12 Months Ended
Mar. 31, 2017
Mar. 31, 2018
Dec. 31, 2017
2017 Debt      
Class of Warrant or Right [Line Items]      
Exercise price (in dollars per share) $ 2.82 $ 2.82 $ 2.82
Expected life (years) 7 years 5 years 11 months 23 days 6 years 2 months 19 days
Expected volatility 74.61% 73.43% 74.18%
Risk-free interest rate 2.22% 2.56% 2.33%
Expected dividend yield 0.00% 0.00% 0.00%
2016 Offerings      
Class of Warrant or Right [Line Items]      
Exercise price (in dollars per share) $ 2.25 $ 2.25 $ 2.25
Expected life (years) 4 years 9 months 15 days 3 years 9 months 29 days 4 years 29 days
Expected volatility 76.29% 100.00% 73.44%
Risk-free interest rate 1.94% 2.39% 2.11%
Expected dividend yield 0.00% 0.00% 0.00%
2017 Offering      
Class of Warrant or Right [Line Items]      
Exercise price (in dollars per share)   $ 2.36 $ 2.36
Expected life (years)   1 year 2 months 9 days 1 year 5 months 5 days
Expected volatility   76.78% 77.55%
Risk-free interest rate   2.09% 1.83%
Expected dividend yield   0.00% 0.00%